13 Types of Retinoids, Do you know them?


13 Types of Retinoids

1. Retinyl Acetate

•A weak retinol ester with little evidence of skin benefits.
•Converts to retinoic acid (active vitamin A) in three steps.
•Best used in combination with stronger retinoids.

2. Retinyl Linoleate

•A weak retinol ester with little evidence of skin benefits.
•Converts to retinoic acid (active vitamin A) in three steps.
•Best used in combination with stronger retinoids.

3. Retinyl Palmitate

•A weak retinol ester.
•Converts to retinoic acid (active vitamin A) in three steps.
•In higher concentrations, may help to treat sun damage and increase skin thickness.

4. Retinyl Propionate

•The most effective retinol ester.
•Converts to retinoic acid (active vitamin A) in three steps.
•In higher concentrations, may help to reduce fine lines and wrinkles and fade pigmentation.

5. Retionl

•Vitamin A, the most proven over-the-counter anti-ageing ingredient.
•Converts to retinoic acid (active vitamin A) in two steps.
•Significantly reduces fine lines and wrinkles.
•Also helps to fade pigmentation, improve skin elasticity and smooth rough skin texture.

6. Retinaldehyde

•Also known as retinal.
•Converts to retinoic acid (active vitamin A) in one step.
•Works faster than retinol, and maybe more effective.
•Treats sun damage, reduces wrinkles and increases skin thickness and elasticity.
•Also clears acne by fighting bacteria and regulating keratinization.

7. Retinyl Retinoate

•A retinoic acid ester.
•Converts to retinoic acid (active vitamin A) and retinol in one step (and then the retinol further converts later on).
•May be more effective than retinol for reducing wrinkles.
•Clears acne by fighting bacteria and reducing sebum production.
•Associated with little to no irritation.

8. Hydroxypinacolone Retinoate (HPR)

• A retinoic acid ester.
• Binds directly to retinoid receptors (no conversion required).
• Less proven than retinol, but may help to reduce wrinkles, age spots and sun damage.
• Associated with little to no irritation.

9. Adapalene

• A synthetic retinoid.
• Binds directly to select retinoid receptors (no conversion required).
• Clears acne by regulating keratinization, reducing inflammation and inhibiting microcomedone formation.
• Also treats mild to moderate signs of photoaging, including wrinkles.
• Less irritating than tretinoin.

10. Tretinoin

• The most widely prescribed retinoid (also known as Retin-A).
• Pure retinoic acid (no conversion required).
• Significantly reduces fine lines and wrinkles, tightens loose skin, smooths rough skin, fades brown spots and melasma and reduces sallowness.
• Also clears acne by regulating keratinization.
• Associated with significant irritation.
• Available by prescription only.

11. Tzazrotene

• The strongest topical retinoid.
• Binds directly to select retinoid receptors (no conversion required).
• Equally if not more effective than adapalene for treating acne.
• Also reduces wrinkles, fades pigmentation, shrinks pore size, increases epidermal thickness and treats psoriasis.
• Associated with significant irritation (more so than tretinoin).
• Available by prescription only.

12. Trifarotene

• The newest retinoid.
• Binds directly to just one retinoid receptor (no conversion required).
• Reduces inflammatory acne on the face, chest shoulders and back.
• Less irritating than tretinoin and adapalene.
• Available by prescription only.

13. Isotretinoin

• An oral retinoid (also known as Accutane).
• Pure retinoic acid (no conversion required).
• Treats severe acne by dramatically reducing sebum production, slowing down skin cell shedding and making sebaceous ducts inhospitable to acne bacteria.
• Associated with many serious side effects.
• Available by prescription only.


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